Avlasevich, Svetlana : rechercher sur Z-Library

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1

Cyclophosphamide and etoposide canine studies demonstrate the cross-species potential of the flow cytometric peripheral blood micronucleated reticulocyte endpoint

Marie McKeon, Yong Xu, David Kirkland, Gabriele Schmuck, Niels Krebsfänger, Svetlana L. Avlasevich, Stephen D. Dertinger

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2012

Langue:

english

Fichier:

PDF, 466 KB

english, 2012

2

Human blood PIGâA mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intraâ and interâsubject variation

Torous, Dorothea K., Avlasevich, Svetlana L., Khattab, Mona G., Baig, Ayesha, Saubermann, Lawrence J., Chen, Yuhchyau, Bemis, Jeffrey C., Lovell, David P., Walker, Vernon E., MacGregor, James T., Dert

Journal:

Environmental and Molecular Mutagenesis

Année:

2020

Fichier:

PDF, 4.85 MB

2020

3

Three-color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood

Stephen D. Dertinger, Kevin Camphausen, James T. MacGregor, Michelle E. Bishop, Dorothea K. Torous, Svetlana Avlasevich, Siân Cairns, Carol R. Tometsko, Cynthia Menard, Thierry Muanza, Yuhchyau Chen,

Journal:

Environmental and Molecular Mutagenesis

Année:

2004

Langue:

english

Fichier:

PDF, 200 KB

english, 2004

4

In vitro micronucleus scoring by flow cytometry: Differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability

Svetlana L. Avlasevich, Steven M. Bryce, Siân E. Cairns, Stephen D. Dertinger

Journal:

Environmental and Molecular Mutagenesis

Année:

2006

Langue:

english

Fichier:

PDF, 440 KB

english, 2006

5

High content flow cytometric micronucleus scoring method is applicable to attachment cell lines

Steven M. Bryce, Jing Shi, John Nicolette, Marilyn Diehl, Paul Sonders, Svetlana Avlasevich, Sarojini Raja, Jeffrey C. Bemis, Stephen D. Dertinger

Journal:

Environmental and Molecular Mutagenesis

Année:

2010

Langue:

english

Fichier:

PDF, 152 KB

english, 2010

6

Miniaturized flow cytometry-based CHO-K1 micronucleus assay discriminates aneugenic and clastogenic modes of action

Steven M. Bryce, Svetlana L. Avlasevich, Jeffrey C. Bemis, Stephen D. Dertinger

Journal:

Environmental and Molecular Mutagenesis

Année:

2011

Langue:

english

Fichier:

PDF, 93 KB

english, 2011

7

Interlaboratory Pig-a gene mutation assay trial: Studies of 1,3-propane sultone with immunomagnetic enrichment of mutant erythrocytes

Stephen D. Dertinger, Souk Phonethepswath, Pamela Weller, Svetlana Avlasevich, Dorothea K. Torous, Jared A. Mereness, Steven M. Bryce, Jeffrey C. Bemis, Sara Bell, Susan Portugal, Michael Aylott, Jame

Journal:

Environmental and Molecular Mutagenesis

Année:

2011

Langue:

english

Fichier:

PDF, 372 KB

english, 2011

8

In vivo flow cytometric Pig-a and micronucleus assays: Highly sensitive discrimination of the carcinogen/noncarcinogen pair benzo(a)pyrene and pyrene using acute and repeated-dose designs

Dorothea K. Torous, Souk Phonethepswath, Svetlana L. Avlasevich, Jared Mereness, Steven M. Bryce, Jeffrey C. Bemis, Pamela Weller, Sara Bell, Carol Gleason, Laura L. Custer, James T. MacGregor, Stephe

Journal:

Environmental and Molecular Mutagenesis

Année:

2012

Langue:

english

Fichier:

PDF, 519 KB

english, 2012

9

Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage

Stephen D. Dertinger, Richard K. Miller, Kelly Brewer, Therese Smudzin, Dorothea K. Torous, Daniel J. Roberts, Svetlana L. Avlasevich, Steven M. Bryce, Siva Sugunan, Yuhchyau Chen

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2007

Langue:

english

Fichier:

PDF, 479 KB

english, 2007

10

In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity

Steven M. Bryce, Jeffrey C. Bemis, Svetlana L. Avlasevich, Stephen D. Dertinger

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2007

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2007

11

Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay

Steven M. Bryce, Svetlana L. Avlasevich, Jeffrey C. Bemis, Magdalena Lukamowicz, Azeddine Elhajouji, Freddy Van Goethem, Marlies De Boeck, Dominiek Beerens, Hilde Aerts, Jacky Van Gompel, Joanne E. Co

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2008

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2008

12

Assessment of genotoxicity associated with hydroxyurea therapy in children with sickle cell anemia

Jonathan M. Flanagan, Thad A. Howard, Nicole Mortier, Svetlana L. Avlasevich, Matthew P. Smeltzer, Song Wu, Stephen D. Dertinger, Russell E. Ware

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2010

Langue:

english

Fichier:

PDF, 411 KB

english, 2010

13

When pigs fly: Immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis

Stephen D. Dertinger, Steven M. Bryce, Souk Phonethepswath, Svetlana L. Avlasevich

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2011

Langue:

english

Fichier:

PDF, 1017 KB

english, 2011

14

Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose–response relationships

Steven M. Bryce, Svetlana L. Avlasevich, Jeffrey C. Bemis, Souk Phonethepswath, Stephen D. Dertinger

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2010

Langue:

english

Fichier:

PDF, 978 KB

english, 2010

15

In vitro micronucleus testing by flow cytometry: Greater throughput, high information content

Steven Bryce, Svetlana Avlasevich, Jeff Bemis, Stephen Dertinger, Sarojini Raja

Journal:

Toxicology Letters

Année:

2009

Langue:

english

Fichier:

PDF, 64 KB

english, 2009

16

Multi-lab validation of an improved flow cytometric in vitro micronucleus assay using attached cell lines

Robert Young, Jing Shi, Steven Bryce, John Nicolette, Marilyn Diehl, Paul Sonder, Souk Phonethepswath, Svetlana Avlasevich, Sarojini Raja, Jeffrey Bemis, Stephen Dertinger, John Nicholette

Journal:

Toxicology Letters

Année:

2009

Langue:

english

Fichier:

PDF, 67 KB

english, 2009

17

Micronucleus and mutation assessment by flow cytometry: Integration into rodent repeat-dose studies

Jeffrey Bemis, Souk Phonethepswath, Dean Franklin, Sarojini Raja, Dorothea Torous, Steven Bryce, Svetlana Avlasevich, Stephen Dertinger

Journal:

Toxicology Letters

Année:

2009

Langue:

english

Fichier:

PDF, 65 KB

english, 2009

18

Flow cytometric 96-well microplate-based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment

Bryce, Steven M., Avlasevich, Svetlana L., Bemis, Jeffrey C., Tate, Matthew, Walmsley, Richard M., Saad, Frédéric, Van Dijck, Kris, De Boeck, Marlies, Van Goethem, Freddy, Lukamowicz-Rajska, Magdalena

Journal:

Environmental and Molecular Mutagenesis

Année:

2013

Langue:

english

Fichier:

PDF, 613 KB

english, 2013

19

Diethylnitrosamine genotoxicity evaluated in sprague dawley rats using Pig-a mutation and reticulocyte micronucleus assays

Avlasevich, Svetlana L., Phonethepswath, Souk, Labash, Carson, Carlson, Kristine, Torous, Dorothea K., Cottom, John, Bemis, Jeffrey C., MacGregor, James T., Dertinger, Stephen D.

Journal:

Environmental and Molecular Mutagenesis

Année:

2014

Langue:

english

Fichier:

PDF, 313 KB

english, 2014

20

Integration of cII and Pig-a mutation and micronucleus endpoints into the Big Blue® transgenic mouse mutation assay: Results for benzo(a)pyrene (BaP) and n-ethyl-n-nitrosourea (ENU)

Young, Robert, Dinesdurage, Harshini, Bruning, David, Stankowski, Leon, Kulkarni, Rohan, Lawlor, Timothy, McKeon, Marie, Xu, Yong, Avlasevich, Svetlana, Torous, Dorothea, Dertinger, Stephen, Aardema,

Journal:

Toxicology Letters

Année:

2014

Langue:

english

Fichier:

PDF, 93 KB

english, 2014

21

Pig-a gene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3-propane sultone

Dertinger, Stephen D., Phonethepswath, Souk, Avlasevich, Svetlana L., Torous, Dorothea K., Mereness, Jared, Cottom, John, Bemis, Jeffrey C., MacGregor, James T.

Journal:

Environmental and Molecular Mutagenesis

Année:

2014

Langue:

english

Fichier:

PDF, 515 KB

english, 2014

22

Flow cytometric analysis of Pig-a gene mutation and chromosomal damage induced by procarbazine hydrochloride in CD-1 mice

Phonethepswath, Souk, Avlasevich, Svetlana L., Torous, Dorothea K., Mereness, Jared, Bemis, Jeffrey C., MacGregor, James T., Dertinger, Stephen D.

Journal:

Environmental and Molecular Mutagenesis

Année:

2013

Langue:

english

Fichier:

PDF, 133 KB

english, 2013

23

Induction of Pig-a mutant erythrocytes in male and female rats exposed to 1,3-propane sultone, ethyl carbamate, or thiotepa

Labash, Carson, Carlson, Kristine, Avlasevich, Svetlana L., Berg, Ariel, Bemis, Jeffrey C., MacGregor, James T., Dertinger, Stephen D.

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2015

Langue:

english

Fichier:

PDF, 943 KB

english, 2015

24

Mouse Pig-a and micronucleus assays respond to N -ethyl- N -nitrosourea, benzo[ a ]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate

Labash, Carson, Avlasevich, Svetlana L., Carlson, Kristine, Berg, Ariel, Torous, Dorothea K., Bryce, Steven M., Bemis, Jeffrey C., MacGregor, James T., Dertinger, Stephen D.

Journal:

Environmental and Molecular Mutagenesis

Année:

2016

Langue:

english

Fichier:

PDF, 1001 KB

english, 2016

25

Genetic Toxicology Testing || List of Contributors

Avlasevich, Svetlana L.

Année:

2016

Langue:

english

Fichier:

PDF, 21 KB

english, 2016

26

Human erythrocyte PIG -A assay: An easily monitored index of gene mutation requiring low volume blood samples

Dertinger, Stephen D., Avlasevich, Svetlana L., Bemis, Jeffrey C., Chen, Yuhchyau, MacGregor, James T.

Journal:

Environmental and Molecular Mutagenesis

Année:

2015

Langue:

english

Fichier:

PDF, 366 KB

english, 2015

27

Diet-induced obesity increases the frequency of Pig-a mutant erythrocytes in male C57BL/6J mice

Wickliffe, Jeffrey K., Dertinger, Stephen D., Torous, Dorothea K., Avlasevich, Svetlana L., Simon-Friedt, Bridget R., Wilson, Mark J.

Journal:

Environmental and Molecular Mutagenesis

Année:

2016

Langue:

english

Fichier:

PDF, 264 KB

english, 2016

28

In vivo pig-a and micronucleus study of the prototypical aneugen vinblastine sulfate

Avlasevich, Svetlana L., Labash, Carson, Torous, Dorothea K., Bemis, Jeffrey C., MacGregor, James T., Dertinger, Stephen D.

Journal:

Environmental and Molecular Mutagenesis

Année:

2017

Langue:

english

Fichier:

PDF, 412 KB

english, 2017

29

Glycosylphosphatidylinositol (GPI) anchored protein deficiency serves as a reliable reporter of Pig-a gene Mutation: Support from an in vitro assay based on L5178Y/ Tk +/− cells and the CD90.2 antigen

Bemis, Jeffrey C., Avlasevich, Svetlana L., Labash, Carson, McKinzie, Page, Revollo, Javier, Dobrovolsky, Vasily N., Dertinger, Stephen D.

Journal:

Environmental and Molecular Mutagenesis

Année:

2017

Langue:

english

Fichier:

PDF, 785 KB

english, 2017

30

Flow cytometric method for scoring rat liver micronuclei with simultaneous assessments of hepatocyte proliferation

Avlasevich, Svetlana L., Khanal, Sumee, Singh, Priyanka, Torous, Dorothea K., Bemis, Jeffrey C., Dertinger, Stephen D.

Journal:

Environmental and Molecular Mutagenesis

Année:

2018

Langue:

english

Fichier:

PDF, 805 KB

english, 2018

31

Integration of liver and blood micronucleus and Pig-a gene mutation endpoints into rat 28-day repeat-treatment studies: Proof-of-principle with diethylnitrosamine

Khanal, Sumee, Singh, Priyanka, Avlasevich, Svetlana L., Torous, Dorothea K., Bemis, Jeffrey C., Dertinger, Stephen D.

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Année:

2018

Langue:

english

Fichier:

PDF, 541 KB

english, 2018

32

Suitability of Long-Term Frozen Rat Blood Samples for the Interrogation of Pig-a Gene Mutation by Flow Cytometry

Avlasevich, Svetlana L., Torous, Dorothea K., Bemis, Jeffrey C., Bhalli, Javed A., Tebbe, Cameron C., Noteboom, Jessica, Thomas, Demetria, Roberts, Daniel J., Barragato, Matthew, Schneider, Brett, Pra

Journal:

Environmental and Molecular Mutagenesis

Année:

2018

Langue:

english

Fichier:

PDF, 480 KB

english, 2018

33

3Rs Friendly Study Designs Facilitate Rat Liver and Blood Micronucleus Assays and Pig‐a Gene Mutation Assessments: Proof‐of‐Concept with Thirteen Reference Chemicals

Dertinger, Stephen D., Avlasevich, Svetlana L., Torous, Dorothea K., Singh, Priyanka, Khanal, Sumee, Kirby, Christopher, Drake, Amanda, MacGregor, James T., Bemis, Jeffrey C.

Journal:

Environmental and Molecular Mutagenesis

Année:

2019

Langue:

english

Fichier:

PDF, 6.92 MB

english, 2019

34

3Rs Friendly Study Designs Facilitate Rat Liver and Blood Micronucleus Assays and Pig‐a Gene Mutation Assessments: Proof‐of‐Concept with Thirteen Reference Chemicals

Dertinger, Stephen D., Avlasevich, Svetlana L., Torous, Dorothea K., Singh, Priyanka, Khanal, Sumee, Kirby, Christopher, Drake, Amanda, MacGregor, James T., Bemis, Jeffrey C.

Journal:

Environmental and Molecular Mutagenesis

Année:

2019

Fichier:

PDF, 6.92 MB

2019

35

Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays

Kirby, Christopher, Baig, Ayesha, Avlasevich, Svetlana L, Torous, Dorothea K, Tian, Shuchang, Singh, Priyanka, Bemis, Jeffrey C, Saubermann, Lawrence J, Dertinger, Stephen D

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2020

36

Intra- and inter-laboratory reproducibility of the rat blood Pig-a gene mutation assay

Dertinger, Stephen D., Avlasevich, Svetlana L., Torous, Dorothea K., Bemis, Jeffrey C., Hove, Tamsanqa Tafara, O'Connell, Oliver, Martus, Hansjoerg, Elhajouji, Azeddine

Journal:

Environmental and Molecular Mutagenesis

Année:

2020

Fichier:

PDF, 2.15 MB

2020

37

Assessment of Systemic Genetic Damage in Pediatric Inflammatory Bowel Disease

Baig, Ayesha, Avlasevich, Svetlana L., Torous, Dorothea K., Bemis, Jeffrey C., Saubermann, Lawrence J., Lovell, David P., MacGregor, James T., Dertinger, Stephen D.

Journal:

Environmental and Molecular Mutagenesis

Année:

2020

Fichier:

PDF, 1.50 MB

2020